Asthma is an inflammatory disease with recurrent exacerbations. Asthma exacerbations are associated to increased inflammation of the airways; in predisposed subjects, exacerbation can be caused by respiratory infections or allergen exposition.
Fluoroquinolones are wide-spectrum antibiotics largely used for treating infections – complicated and not – caused by susceptible bacteria.
Even though they appear to be well tolerated, fluoroquinolones have been associated to several adverse reactions clinically relevant and potentially detrimental for health, among which cardiovascular (QT interval prolongation and “torsades de pointes”) and metabolic ones (hypo and hyperglycaemia), discussed in this article.
Possible arrhythmogenic risk
In the last ten years, atypical antipsychotics progressively substituted first generation drugs thanks to a more favourable tolerability profile, particularly for the minor frequency of neurological extrapyramidal effects.1 Atypical antipsychotics have been widely used for few years also in paediatrics for treating children and teenagers with psychotics and behavioural disturbances. However, officially acknowledged indications for paediatric use are limited.
Analysis found these products to contain undeclared Sildenafil and/or Tadalafil, may interact with nitrates found in some prescription drugs, and may lower blood pressure to dangerous levels.
Ventilator may stop functioning, triggering the safety alarm and causing the patient to suddenly be required to breathe on his or her own.
Il Comitato di Valutazione dei Rischi per la Farmacovigilanza (PRAC) raccomanda la sospensione dell’uso di Protelor/Osseor (stronzio ranelato) per il trattamento dell’osteoporosi.
Safety Labeling Changes includes 39 products with revisions to Prescribing Information.
L’Agenzia Italiana del Farmaco, in accordo con l’Agenzia Europea dei
Medicinali, rende disponibili nuove ed importanti informazioni sul rischio di errori nel dosaggio di Pixuvri (pixantrone).
80.211.154.110
