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Enoxaparin and kidney failure
Drug Indications
Enoxaparin is a low molecular weight heparin (LMWH) that is widely used in clinical practice. The treatment indications are:
Inglese
Drug Indications
Enoxaparin is a low molecular weight heparin (LMWH) that is widely used in clinical practice. The treatment indications are:
Direct oral anticoagulants (DOACs), also known as New Oral Anticoagulants (NAOs), have for the first time provided a therapeutic alternative to vitamin K antagonists (VKAs), of which warfarin is the prototype, indicating neither inferiority nor superiority in the prevention of stroke in case of non-valvular atrial fibrillation.
In un articolo apparso su Focus Farmacovigilanza nel 2014 sono stati discussi i principali effetti avversi dei farmaci antiepilettici.1 In tale articolo veniva sottolineato come l’assunzione di questi farmaci durante la gravidanza possa comportare un aumento del rischio di malformazioni fetali e come l’entità di questo rischio vari in rapporto al tipo e alla dose del farmaco somministrato.
Requiring a new warning about this risk to be added to the prescribing information of all SGLT2 inhibitors and to the patient Medication Guide.
FDA has reviewed the final results from the post-approval study conducted by SynCardia Systems, LLC. for their Temporary Total Artificial Heart (TAH-t) Companion 2 Driver System (C2 Driver System). These final results indicate a higher mortality rate and higher stroke rate for patients initially supported with the C2 Driver System compared to patients initially supported with the previous generation driver, the Circulatory Support System (CSS) Console.
The FDA is reminding health care providers that tests to detect rupture of the amniotic membranes should not be used without other clinical assessments to make critical patient management decisions.
L'Agenzia Italiana
del Farmaco (AIFA) rende disponibili nuove importanti informazioni di sicurezza riguardanti le nuove controindicazioni relative all’utilizzo dei farmaci contenenti retinoidi.
The antibiotic Zithromax, Zmax (azithromycin) should not be given long-term to prevent a certain inflammatory lung condition in patients with cancers of the blood or lymph nodes who undergo a donor stem cell transplant. Results of a clinical trial found an increased rate of relapse in cancers affecting the blood and lymph nodes, including death, in these patients.
Ventiquattro anni, cento numeri. Nata nel lontano maggio del 1994 quest’anno Focus Farmacovigilanza ora Focus Famarcovigilanza Newsletter raggiunge il traguardo del centesimo numero. Per iniziativa del professor Giampaolo Velo (fondatore e direttore della rivista fino alla sua scomparsa nel 2017) e del suo gruppo sin dai primi passi la rivista è nata come bollettino di divulgazione medico-scientifica nel campo della farmacovigilanza ed ha presto aderitoall’ISDB, l’associazione internazionale dei bollettini indipendenti (http://www.isdbweb.org/).
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