Canagliflozin (Invokana, Invokamet): Drug Safety Communication - Increased Risk of Leg and Foot Amputations New warnings, including a Boxed Warning, to be added to the canagliflozin drug labels. Lingua Italiano Leggi tutto su Canagliflozin (Invokana, Invokamet): Drug Safety Communication - Increased Risk of Leg and Foot Amputations